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Sorbs1 and -2 Interact with CrkL and Are Required for Acetylcholine Receptor Cluster Formation

Crk and CrkL are noncatalytic adaptor proteins necessary for the formation of neuromuscular synapses which function downstream of muscle-specific kinase (MuSK), a receptor tyrosine kinase expressed in skeletal muscle, and the MuSK binding protein Dok-7. How Crk/CrkL regulate neuromuscular endplate f...

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Detalles Bibliográficos
Autores principales: Hallock, Peter T., Chin, Sherry, Blais, Steven, Neubert, Thomas A., Glass, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719301/
https://www.ncbi.nlm.nih.gov/pubmed/26527617
http://dx.doi.org/10.1128/MCB.00775-15