Rapid evolutionary turnover underlies conserved lncRNA–genome interactions

Many long noncoding RNAs (lncRNAs) can regulate chromatin states, but the evolutionary origin and dynamics driving lncRNA–genome interactions are unclear. We adapted an integrative strategy that identifies lncRNA orthologs in different species despite limited sequence similarity, which is applicable...

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Detalles Bibliográficos
Autores principales: Quinn, Jeffrey J., Zhang, Qiangfeng C., Georgiev, Plamen, Ilik, Ibrahim A., Akhtar, Asifa, Chang, Howard Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719309/
https://www.ncbi.nlm.nih.gov/pubmed/26773003
http://dx.doi.org/10.1101/gad.272187.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719309/
https://www.ncbi.nlm.nih.gov/pubmed/26773003
http://dx.doi.org/10.1101/gad.272187.115

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