MMP-9 facilitates selective proteolysis of the histone H3 tail at genes necessary for proficient osteoclastogenesis

Although limited proteolysis of the histone H3 N-terminal tail (H3NT) is frequently observed during mammalian differentiation, the specific genomic sites targeted for H3NT proteolysis and the functional significance of H3NT cleavage remain largely unknown. Here we report the first method to identify...

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Detalles Bibliográficos
Autores principales: Kim, Kyunghwan, Punj, Vasu, Kim, Jin-Man, Lee, Sunyoung, Ulmer, Tobias S., Lu, Wange, Rice, Judd C., An, Woojin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719310/
https://www.ncbi.nlm.nih.gov/pubmed/26744418
http://dx.doi.org/10.1101/gad.268714.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719310/
https://www.ncbi.nlm.nih.gov/pubmed/26744418
http://dx.doi.org/10.1101/gad.268714.115

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