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Essential Nonredundant Function of the Catalytic Activity of Histone Deacetylase 2 in Mouse Development
The class I histone deacetylases (HDACs) HDAC1 and HDAC2 play partially redundant roles in the regulation of gene expression and mouse development. As part of multisubunit corepressor complexes, these two deacetylases exhibit both enzymatic and nonenzymatic functions. To examine the impact of the ca...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719423/ https://www.ncbi.nlm.nih.gov/pubmed/26598605 http://dx.doi.org/10.1128/MCB.00639-15 |