Essential Nonredundant Function of the Catalytic Activity of Histone Deacetylase 2 in Mouse Development

The class I histone deacetylases (HDACs) HDAC1 and HDAC2 play partially redundant roles in the regulation of gene expression and mouse development. As part of multisubunit corepressor complexes, these two deacetylases exhibit both enzymatic and nonenzymatic functions. To examine the impact of the ca...

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Detalles Bibliográficos
Autores principales: Hagelkruys, Astrid, Mattes, Katharina, Moos, Verena, Rennmayr, Magdalena, Ringbauer, Manuela, Sawicka, Anna, Seiser, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719423/
https://www.ncbi.nlm.nih.gov/pubmed/26598605
http://dx.doi.org/10.1128/MCB.00639-15

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