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Combinatorial engineering of hybrid mevalonate pathways in Escherichiacoli for protoilludene production

BACKGROUND: Protoilludene is a valuable sesquiterpene and serves as a precursor for several medicinal compounds and antimicrobial chemicals. It can be synthesized by heterologous expression of protoilludene synthase in Escherichiacoli with overexpression of mevalonate (MVA) or methylerythritol-phosp...

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Detalles Bibliográficos
Autores principales: Yang, Liyang, Wang, Chonglong, Zhou, Jia, Kim, Seon-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719686/
https://www.ncbi.nlm.nih.gov/pubmed/26785630
http://dx.doi.org/10.1186/s12934-016-0409-7