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Combinatorial engineering of hybrid mevalonate pathways in Escherichiacoli for protoilludene production
BACKGROUND: Protoilludene is a valuable sesquiterpene and serves as a precursor for several medicinal compounds and antimicrobial chemicals. It can be synthesized by heterologous expression of protoilludene synthase in Escherichiacoli with overexpression of mevalonate (MVA) or methylerythritol-phosp...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719686/ https://www.ncbi.nlm.nih.gov/pubmed/26785630 http://dx.doi.org/10.1186/s12934-016-0409-7 |