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B-cell and T-cell quantification in minor salivary glands in primary Sjögren’s syndrome: development and validation of a pixel-based digital procedure

BACKGROUND: Evaluating lymphocytic infiltration of minor salivary gland biopsy in primary Sjögren’s syndrome is challenging. We developed and evaluated a digital method for quantifying B and T lymphocytes in whole minor salivary gland biopsy slides. METHODS: Minor salivary gland biopsies were immuno...

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Detalles Bibliográficos
Autores principales: Costa, Sebastian, Schutz, Sacha, Cornec, Divi, Uguen, Arnaud, Quintin-Roué, Isabelle, Lesourd, Agnès, Berthelot, Jean-Marie, Hachulla, Eric, Hatron, Pierre-Yves, Goeb, Vincent, Vittecoq, Olivier, Pers, Jacques Olivier, Marcorelles, Pascale, Saraux, Alain, Devauchelle-Pensec, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719698/
https://www.ncbi.nlm.nih.gov/pubmed/26785742
http://dx.doi.org/10.1186/s13075-016-0924-2