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B-cell and T-cell quantification in minor salivary glands in primary Sjögren’s syndrome: development and validation of a pixel-based digital procedure
BACKGROUND: Evaluating lymphocytic infiltration of minor salivary gland biopsy in primary Sjögren’s syndrome is challenging. We developed and evaluated a digital method for quantifying B and T lymphocytes in whole minor salivary gland biopsy slides. METHODS: Minor salivary gland biopsies were immuno...
Autores principales: | Costa, Sebastian, Schutz, Sacha, Cornec, Divi, Uguen, Arnaud, Quintin-Roué, Isabelle, Lesourd, Agnès, Berthelot, Jean-Marie, Hachulla, Eric, Hatron, Pierre-Yves, Goeb, Vincent, Vittecoq, Olivier, Pers, Jacques Olivier, Marcorelles, Pascale, Saraux, Alain, Devauchelle-Pensec, Valérie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719698/ https://www.ncbi.nlm.nih.gov/pubmed/26785742 http://dx.doi.org/10.1186/s13075-016-0924-2 |
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