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Early changes in blood-based joint tissue destruction biomarkers are predictive of response to tocilizumab in the LITHE study

BACKGROUND: Rheumatoid arthritis (RA) is characterized by gradual joint destruction. Tocilizumab (TCZ) significantly suppresses symptoms, however not all patients are protected from joint damage. We investigated whether early measurement of specific biomarkers could predict early joint protection re...

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Detalles Bibliográficos
Autores principales: Bay-Jensen, Anne C., Platt, Adam, Siebuhr, Anne Sofie, Christiansen, Claus, Byrjalsen, Inger, Karsdal, Morten A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719735/
https://www.ncbi.nlm.nih.gov/pubmed/26787505
http://dx.doi.org/10.1186/s13075-015-0913-x