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Early changes in blood-based joint tissue destruction biomarkers are predictive of response to tocilizumab in the LITHE study
BACKGROUND: Rheumatoid arthritis (RA) is characterized by gradual joint destruction. Tocilizumab (TCZ) significantly suppresses symptoms, however not all patients are protected from joint damage. We investigated whether early measurement of specific biomarkers could predict early joint protection re...
Autores principales: | Bay-Jensen, Anne C., Platt, Adam, Siebuhr, Anne Sofie, Christiansen, Claus, Byrjalsen, Inger, Karsdal, Morten A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719735/ https://www.ncbi.nlm.nih.gov/pubmed/26787505 http://dx.doi.org/10.1186/s13075-015-0913-x |
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