OPTIMA: sensitive and accurate whole-genome alignment of error-prone genomic maps by combinatorial indexing and technology-agnostic statistical analysis

BACKGROUND: Resolution of complex repeat structures and rearrangements in the assembly and analysis of large eukaryotic genomes is often aided by a combination of high-throughput sequencing and genome-mapping technologies (for example, optical restriction mapping). In particular, mapping technologie...

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Detalles Bibliográficos
Autores principales: Verzotto, Davide, M. Teo, Audrey S., Hillmer, Axel M., Nagarajan, Niranjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719737/
https://www.ncbi.nlm.nih.gov/pubmed/26793302
http://dx.doi.org/10.1186/s13742-016-0110-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719737/
https://www.ncbi.nlm.nih.gov/pubmed/26793302
http://dx.doi.org/10.1186/s13742-016-0110-0

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