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An integrated Taguchi and response surface methodological approach for the optimization of an HPLC method to determine glimepiride in a supersaturatable self-nanoemulsifying formulation

We studied the application of Taguchi orthogonal array (TOA) design during the development of an isocratic stability indicating HPLC method for glimepiride as per TOA design; twenty-seven experiments were conducted by varying six chromatographic factors. Percentage of organic phase was the most sign...

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Detalles Bibliográficos
Autores principales: Dash, Rajendra Narayan, Mohammed, Habibuddin, Humaira, Touseef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720010/
https://www.ncbi.nlm.nih.gov/pubmed/26903773
http://dx.doi.org/10.1016/j.jsps.2015.03.004