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An integrated Taguchi and response surface methodological approach for the optimization of an HPLC method to determine glimepiride in a supersaturatable self-nanoemulsifying formulation

We studied the application of Taguchi orthogonal array (TOA) design during the development of an isocratic stability indicating HPLC method for glimepiride as per TOA design; twenty-seven experiments were conducted by varying six chromatographic factors. Percentage of organic phase was the most sign...

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Detalles Bibliográficos
Autores principales:	Dash, Rajendra Narayan, Mohammed, Habibuddin, Humaira, Touseef
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720010/ https://www.ncbi.nlm.nih.gov/pubmed/26903773 http://dx.doi.org/10.1016/j.jsps.2015.03.004

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