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Development and evaluation of natural gum-based extended release matrix tablets of two model drugs of different water solubilities by direct compression
The study was aimed at developing extended release matrix tablets of poorly water-soluble diclofenac sodium and highly water-soluble metformin hydrochloride by direct compression using cashew gum, xanthan gum and hydroxypropylmethylcellulose (HPMC) as release retardants. The suitability of light gra...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720012/ https://www.ncbi.nlm.nih.gov/pubmed/26903772 http://dx.doi.org/10.1016/j.jsps.2015.03.005 |