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Development and evaluation of natural gum-based extended release matrix tablets of two model drugs of different water solubilities by direct compression

The study was aimed at developing extended release matrix tablets of poorly water-soluble diclofenac sodium and highly water-soluble metformin hydrochloride by direct compression using cashew gum, xanthan gum and hydroxypropylmethylcellulose (HPMC) as release retardants. The suitability of light gra...

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Detalles Bibliográficos
Autores principales: Ofori-Kwakye, Kwabena, Mfoafo, Kwadwo Amanor, Kipo, Samuel Lugrie, Kuntworbe, Noble, Boakye-Gyasi, Mariam El
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720012/
https://www.ncbi.nlm.nih.gov/pubmed/26903772
http://dx.doi.org/10.1016/j.jsps.2015.03.005