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Fetal Hematopoietic Stem Cell Transplantation Fails to Fully Regenerate the B-Lymphocyte Compartment

B cells are key components of cellular and humoral immunity and, like all lymphocytes, are thought to originate and renew from hematopoietic stem cells (HSCs). However, our recent single-HSC transfer studies demonstrate that adult bone marrow HSCs do not regenerate B-1a, a subset of tissue B cells r...

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Detalles Bibliográficos
Autores principales: Ghosn, Eliver Eid Bou, Waters, Jeffrey, Phillips, Megan, Yamamoto, Ryo, Long, Brian R., Yang, Yang, Gerstein, Rachel, Stoddart, Cheryl A., Nakauchi, Hiromitsu, Herzenberg, Leonore A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720028/
https://www.ncbi.nlm.nih.gov/pubmed/26724903
http://dx.doi.org/10.1016/j.stemcr.2015.11.011