Cargando…
Fetal Hematopoietic Stem Cell Transplantation Fails to Fully Regenerate the B-Lymphocyte Compartment
B cells are key components of cellular and humoral immunity and, like all lymphocytes, are thought to originate and renew from hematopoietic stem cells (HSCs). However, our recent single-HSC transfer studies demonstrate that adult bone marrow HSCs do not regenerate B-1a, a subset of tissue B cells r...
Autores principales: | Ghosn, Eliver Eid Bou, Waters, Jeffrey, Phillips, Megan, Yamamoto, Ryo, Long, Brian R., Yang, Yang, Gerstein, Rachel, Stoddart, Cheryl A., Nakauchi, Hiromitsu, Herzenberg, Leonore A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720028/ https://www.ncbi.nlm.nih.gov/pubmed/26724903 http://dx.doi.org/10.1016/j.stemcr.2015.11.011 |
Ejemplares similares
-
Selective uptake of single walled carbon nanotubes by circulating
monocytes for enhanced tumour delivery
por: Smith, Bryan Ronain, et al.
Publicado: (2014) -
Development of B Cells and Erythrocytes Is Specifically Impaired by the Drug Celastrol in Mice
por: Kusy, Sophie, et al.
Publicado: (2012) -
Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment
por: Morita, Yohei, et al.
Publicado: (2010) -
Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment
por: Yamamoto, Ryo, et al.
Publicado: (2018) -
Distinct mechanisms define murine B cell lineage immunoglobulin heavy chain (IgH) repertoires
por: Yang, Yang, et al.
Publicado: (2015)