Multidimensional Separation Using HILIC and SCX Pre-fractionation for RP LC-MS/MS Platform with Automated Exclusion List-based MS Data Acquisition with Increased Protein Quantification

Liquid chromatography–mass spectrometry (LC-MS) based proteomics is one of the most widely used analytical platforms for global protein discovery and quantification. One of the challenges is the difficulty of identifying low abundance biomarker proteins from limited biological samples. Extensive fra...

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Detalles Bibliográficos
Autores principales: Zhou, Yu, Meng, Zhen, Edman-Woolcott, Maria, Hamm-Alvarez, Sarah F, Zandi, Ebrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720167/
https://www.ncbi.nlm.nih.gov/pubmed/26807013
http://dx.doi.org/10.4172/jpb.1000378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720167/
https://www.ncbi.nlm.nih.gov/pubmed/26807013
http://dx.doi.org/10.4172/jpb.1000378

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