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Brain-Derived Neurotrophic Factor Deficiency Restricts Proliferation of Oligodendrocyte Progenitors Following Cuprizone-Induced Demyelination

Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth factors that through its neurotrophic tyrosine kinase, receptor, type 2 (TrkB) receptor, increases 5-bromo-2-deoxyuridine incorporation in oligodendrocyte progenitor cells (OPCs) in culture. Roles in vivo are l...

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Detalles Bibliográficos
Autores principales: Tsiperson, Vladislav, Huang, Yangyang, Bagayogo, Issa, Song, Yeri, VonDran, Melissa W, DiCicco-Bloom, Emanuel, Dreyfus, Cheryl F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720179/
https://www.ncbi.nlm.nih.gov/pubmed/25586993
http://dx.doi.org/10.1177/1759091414566878