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Pulsatile Hyperglycaemia Induces Vascular Oxidative Stress and GLUT 1 Expression More Potently than Sustained Hyperglycaemia in Rats on High Fat Diet

INTRODUCTION: Pulsatile hyperglycaemia resulting in oxidative stress may play an important role in the development of macrovascular complications. We investigated the effects of sustained vs. pulsatile hyperglycaemia in insulin resistant rats on markers of oxidative stress, enzyme expression and glu...

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Detalles Bibliográficos
Autores principales: Rakipovski, Günaj, Lykkesfeldt, Jens, Raun, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720376/
https://www.ncbi.nlm.nih.gov/pubmed/26790104
http://dx.doi.org/10.1371/journal.pone.0147412