Stat3 Signaling Promotes Survival And Maintenance Of Medullary Thymic Epithelial Cells

Medullary thymic epithelial cells (mTECs) are essential for establishing central tolerance by expressing a diverse array of self-peptides that delete autoreactive thymocytes and/or divert thymocytes into the regulatory T cell lineage. Activation of the NFκB signaling pathway in mTEC precursors is in...

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Detalles Bibliográficos
Autores principales: Lomada, Dakshayani, Jain, Manju, Bolner, Michelle, Reeh, Kaitlin A. G., Kang, Rhea, Reddy, Madhava C., DiGiovanni, John, Richie, Ellen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720390/
https://www.ncbi.nlm.nih.gov/pubmed/26789196
http://dx.doi.org/10.1371/journal.pgen.1005777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720390/
https://www.ncbi.nlm.nih.gov/pubmed/26789196
http://dx.doi.org/10.1371/journal.pgen.1005777

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