Haplotype-Phased Synthetic Long Reads from Short-Read Sequencing

Next-generation DNA sequencing has revolutionized the study of biology. However, the short read lengths of the dominant instruments complicate assembly of complex genomes and haplotype phasing of mixtures of similar sequences. Here we demonstrate a method to reconstruct the sequences of individual n...

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Detalles Bibliográficos
Autores principales: Stapleton, James A., Kim, Jeongwoon, Hamilton, John P., Wu, Ming, Irber, Luiz C., Maddamsetti, Rohan, Briney, Bryan, Newton, Linsey, Burton, Dennis R., Brown, C. Titus, Chan, Christina, Buell, C. Robin, Whitehead, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720449/
https://www.ncbi.nlm.nih.gov/pubmed/26789840
http://dx.doi.org/10.1371/journal.pone.0147229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720449/
https://www.ncbi.nlm.nih.gov/pubmed/26789840
http://dx.doi.org/10.1371/journal.pone.0147229

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