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Haplotype-Phased Synthetic Long Reads from Short-Read Sequencing
Next-generation DNA sequencing has revolutionized the study of biology. However, the short read lengths of the dominant instruments complicate assembly of complex genomes and haplotype phasing of mixtures of similar sequences. Here we demonstrate a method to reconstruct the sequences of individual n...
Autores principales: | Stapleton, James A., Kim, Jeongwoon, Hamilton, John P., Wu, Ming, Irber, Luiz C., Maddamsetti, Rohan, Briney, Bryan, Newton, Linsey, Burton, Dennis R., Brown, C. Titus, Chan, Christina, Buell, C. Robin, Whitehead, Timothy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720449/ https://www.ncbi.nlm.nih.gov/pubmed/26789840 http://dx.doi.org/10.1371/journal.pone.0147229 |
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