Suppression of transcriptional drift extends C. elegans lifespan by postponing the onset of mortality

Longevity mechanisms increase lifespan by counteracting the effects of aging. However, whether longevity mechanisms counteract the effects of aging continually throughout life, or whether they act during specific periods of life, preventing changes that precede mortality is unclear. Here, we uncover...

Descripción completa

Detalles Bibliográficos
Autores principales: Rangaraju, Sunitha, Solis, Gregory M, Thompson, Ryan C, Gomez-Amaro, Rafael L, Kurian, Leo, Encalada, Sandra E, Niculescu, Alexander B, Salomon, Daniel R, Petrascheck, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720515/
https://www.ncbi.nlm.nih.gov/pubmed/26623667
http://dx.doi.org/10.7554/eLife.08833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720515/
https://www.ncbi.nlm.nih.gov/pubmed/26623667
http://dx.doi.org/10.7554/eLife.08833

Ejemplares similares