Functional interplay between ganglioside GM1 and cross‐linking galectin‐1 induces axon‐like neuritogenesis via integrin‐based signaling and TRPC5‐dependent Ca(2+) influx

Axon‐like neuritogenesis in neuroblastoma (NG108‐15) cells and primary cerebellar granular neurons is furthered by the presence of ganglioside GM1. We describe here that galectin‐1 (Gal‐1), a homobivalent endogenous lectin, is an effector by cross‐linking the ganglioside and its associated glycoprot...

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Detalles Bibliográficos
Autores principales: Wu, Gusheng, Lu, Zi‐Hua, André, Sabine, Gabius, Hans‐Joachim, Ledeen, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720552/
https://www.ncbi.nlm.nih.gov/pubmed/26526326
http://dx.doi.org/10.1111/jnc.13418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720552/
https://www.ncbi.nlm.nih.gov/pubmed/26526326
http://dx.doi.org/10.1111/jnc.13418

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