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Functional interplay between ganglioside GM1 and cross‐linking galectin‐1 induces axon‐like neuritogenesis via integrin‐based signaling and TRPC5‐dependent Ca(2+) influx
Axon‐like neuritogenesis in neuroblastoma (NG108‐15) cells and primary cerebellar granular neurons is furthered by the presence of ganglioside GM1. We describe here that galectin‐1 (Gal‐1), a homobivalent endogenous lectin, is an effector by cross‐linking the ganglioside and its associated glycoprot...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720552/ https://www.ncbi.nlm.nih.gov/pubmed/26526326 http://dx.doi.org/10.1111/jnc.13418 |