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Lung epithelial cell-derived extracellular vesicles activate macrophage-mediated inflammatory responses via ROCK1 pathway

Despite decades of research, the pathogenesis of acute respiratory distress syndrome (ARDS) remains poorly understood, thus impeding the development of effective treatment. Diffuse alveolar damage (DAD) and lung epithelial cell death are prominent features of ARDS. Lung epithelial cells are the firs...

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Detalles Bibliográficos
Autores principales: Moon, H-G, Cao, Y, Yang, J, Lee, J H, Choi, H S, Jin, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720875/
https://www.ncbi.nlm.nih.gov/pubmed/26658190
http://dx.doi.org/10.1038/cddis.2015.282