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NFAT4-dependent miR-324-5p regulates mitochondrial morphology and cardiomyocyte cell death by targeting Mtfr1

Emerging evidence suggest that the abnormal mitochondrial fission participates in pathogenesis of cardiac diseases, including myocardial infarction and heart failure. However, the molecular components regulating mitochondrial network in heart remain largely unidentified. Here we report that NFAT4, m...

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Detalles Bibliográficos
Autores principales: Wang, K, Zhang, D-l, Long, B, An, T, Zhang, J, Zhou, L-Y, Liu, C-Y, Li, P-F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720883/
https://www.ncbi.nlm.nih.gov/pubmed/26633713
http://dx.doi.org/10.1038/cddis.2015.348