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Apoptotic cell clearance of Leishmania major-infected neutrophils by dendritic cells inhibits CD8(+) T-cell priming in vitro by Mer tyrosine kinase-dependent signaling

Neutrophils are the predominant recruited and infected cells during the early stages of Leishmania major infection in the skin, and depletion of neutrophils promotes immunity to infection transmitted by sand fly bite. In order to better understand how the acute neutrophilic response suppresses immun...

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Detalles Bibliográficos
Autores principales: Ribeiro-Gomes, F L, Romano, A, Lee, S, Roffê, E, Peters, N C, Debrabant, A, Sacks, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720886/
https://www.ncbi.nlm.nih.gov/pubmed/26658192
http://dx.doi.org/10.1038/cddis.2015.351