Neuroblastoma: oncogenic mechanisms and therapeutic exploitation of necroptosis

Neuroblastoma (NB) is the most common extracranial childhood tumor classified in five stages (1, 2, 3, 4 and 4S), two of which (3 and 4) identify chemotherapy-resistant, highly aggressive disease. High-risk NB frequently displays MYCN amplification, mutations in ALK and ATRX, and genomic rearrangeme...

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Detalles Bibliográficos
Autores principales: Nicolai, S, Pieraccioli, M, Peschiaroli, A, Melino, G, Raschellà, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720889/
https://www.ncbi.nlm.nih.gov/pubmed/26633716
http://dx.doi.org/10.1038/cddis.2015.354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720889/
https://www.ncbi.nlm.nih.gov/pubmed/26633716
http://dx.doi.org/10.1038/cddis.2015.354

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