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Neuroblastoma: oncogenic mechanisms and therapeutic exploitation of necroptosis
Neuroblastoma (NB) is the most common extracranial childhood tumor classified in five stages (1, 2, 3, 4 and 4S), two of which (3 and 4) identify chemotherapy-resistant, highly aggressive disease. High-risk NB frequently displays MYCN amplification, mutations in ALK and ATRX, and genomic rearrangeme...
Autores principales: | Nicolai, S, Pieraccioli, M, Peschiaroli, A, Melino, G, Raschellà, G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720889/ https://www.ncbi.nlm.nih.gov/pubmed/26633716 http://dx.doi.org/10.1038/cddis.2015.354 |
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