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Nucleoprotein of influenza A virus negatively impacts antiapoptotic protein API5 to enhance E2F1-dependent apoptosis and virus replication

Apoptosis of host cells profoundly influences virus propagation and dissemination, events that are integral to influenza A virus (IAV) pathogenesis. The trigger for activation of apoptosis is regulated by an intricate interplay between cellular and viral proteins, with a strong bearing on IAV replic...

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Detalles Bibliográficos
Autores principales: Mayank, A K, Sharma, S, Nailwal, H, Lal, S K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720893/
https://www.ncbi.nlm.nih.gov/pubmed/26673663
http://dx.doi.org/10.1038/cddis.2015.360