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C2238/αANP modulates apolipoprotein E through Egr-1/miR199a in vascular smooth muscle cells in vitro

Subjects carrying the T2238C ANP gene variant have a higher risk to suffer a stroke or myocardial infarction. The mechanisms through which T2238C/αANP exerts detrimental vascular effects need to be fully clarified. In the present work we aimed at exploring the impact of C2238/αANP (mutant form) on a...

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Detalles Bibliográficos
Autores principales: Stanzione, R, Sciarretta, S, Marchitti, S, Bianchi, F, Di Castro, S, Scarpino, S, Cotugno, M, Frati, G, Volpe, M, Rubattu, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720902/
https://www.ncbi.nlm.nih.gov/pubmed/26720342
http://dx.doi.org/10.1038/cddis.2015.370