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The genomic basis of adaptation to the fitness cost of rifampicin resistance in Pseudomonas aeruginosa
Antibiotic resistance carries a fitness cost that must be overcome in order for resistance to persist over the long term. Compensatory mutations that recover the functional defects associated with resistance mutations have been argued to play a key role in overcoming the cost of resistance, but comp...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721101/ https://www.ncbi.nlm.nih.gov/pubmed/26763710 http://dx.doi.org/10.1098/rspb.2015.2452 |