Estrogen receptor α in cancer associated fibroblasts suppresses prostate cancer invasion via reducing CCL5, IL6 and macrophage infiltration in the tumor microenvironment

BACKGROUND: Cancer associated fibroblasts (CAF) play important roles in tumor growth that involves inflammation and epithelial cell differentiation. Early studies suggested that estrogen receptor alpha (ERα) was expressed in stromal cells in normal prostates and prostate cancer (PCa), but the detail...

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Detalles Bibliográficos
Autores principales: Yeh, Chiuan-Ren, Slavin, Spencer, Da, Jun, Hsu, Iawen, Luo, Jie, Xiao, Guang-Qian, Ding, Jie, Chou, Fu-Ju, Yeh, Shuyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721150/
https://www.ncbi.nlm.nih.gov/pubmed/26790618
http://dx.doi.org/10.1186/s12943-015-0488-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721150/
https://www.ncbi.nlm.nih.gov/pubmed/26790618
http://dx.doi.org/10.1186/s12943-015-0488-9

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