Comparisons of biophysical properties and bioactivities of mono-PEGylated endostatin and an endostatin analog

BACKGROUND: Endostatin (ES) is a well-established potent endogenous antiangiogenic factor. An ES variant, called zinc-binding protein-ES (ZBP-ES), is clinically available; however, its use is limited by rapid renal clearance and short residence time. PEGylation has been exploited to overcome these s...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Shan, Fu, Yan, Luo, Yongzhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721152/
https://www.ncbi.nlm.nih.gov/pubmed/26792627
http://dx.doi.org/10.1186/s40880-016-0080-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721152/
https://www.ncbi.nlm.nih.gov/pubmed/26792627
http://dx.doi.org/10.1186/s40880-016-0080-8

Ejemplares similares