Charcot-Marie-Tooth 2b associated Rab7 mutations cause axon growth and guidance defects during vertebrate sensory neuron development

BACKGROUND: Charcot-Marie-Tooth2b (CMT2b) is an axonal form of a human neurodegenerative disease that preferentially affects sensory neurons. CMT2b is dominantly inherited and is characterized by unusually early onset, presenting in the second or third decade of life. Five missense mutations in the...

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Detalles Bibliográficos
Autores principales: Ponomareva, Olga Y., Eliceiri, Kevin W., Halloran, Mary C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721196/
https://www.ncbi.nlm.nih.gov/pubmed/26791407
http://dx.doi.org/10.1186/s13064-016-0058-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721196/
https://www.ncbi.nlm.nih.gov/pubmed/26791407
http://dx.doi.org/10.1186/s13064-016-0058-x

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