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Direct targeting sperm-associated antigen 9 by miR-141 influences hepatocellular carcinoma cell growth and metastasis via JNK pathway

BACKGROUND: The aberrant expression of sperm-associated antigen 9 (SPAG9) is associated with numerous cancers, including hepatocellular carcinoma (HCC). The exploration of molecules and mechanisms regulating SPAG9 expression may provide new options for HCC therapy. METHODS: MiRNA target prediction p...

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Detalles Bibliográficos
Autores principales: Lou, Guohua, Dong, Xuejun, Xia, Caixia, Ye, Bingjue, Yan, Qiuyue, Wu, Shanshan, Yu, Ye, Liu, Feifei, Zheng, Min, Chen, Zhi, Liu, Yanning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721207/
https://www.ncbi.nlm.nih.gov/pubmed/26790956
http://dx.doi.org/10.1186/s13046-016-0289-z