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Alemtuzumab in T-cell large granular lymphocytic leukaemia: a phase 2 study

BACKGROUND: T-cell large granular lymphocytic leukemia (T-LGL) is a lymphoproliferative disease presenting with immune-mediated cytopenias and characterized by clonal expansion of cytotoxic CD3(+)CD8(+) lymphocytes. Methotrexate, cyclosporine, or cyclophosphamide improve cytopenias in 50% of patient...

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Detalles Bibliográficos
Autores principales: Dumitriu, Bogdan, Ito, Sawa, Feng, Xingmin, Stephens, Nicole, Yunce, Muharrem, Kajigaya, Sachiko, Melenhorst, Joseph J., Rios, Olga, Scheinberg, Priscila, Chinian, Fariba, Keyvanfar, Keyvan, Battiwalla, Minoo, Wu, Colin O., Maric, Irina, Xi, Liqiang, Raffeld, Mark, Muranski, Pawel, Townsley, Danielle M., Young, Neal S., Barrett, Austin John, Scheinberg, Phillip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721315/
https://www.ncbi.nlm.nih.gov/pubmed/26765645
http://dx.doi.org/10.1016/S2352-3026(15)00227-6