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Alemtuzumab in T-cell large granular lymphocytic leukaemia: a phase 2 study
BACKGROUND: T-cell large granular lymphocytic leukemia (T-LGL) is a lymphoproliferative disease presenting with immune-mediated cytopenias and characterized by clonal expansion of cytotoxic CD3(+)CD8(+) lymphocytes. Methotrexate, cyclosporine, or cyclophosphamide improve cytopenias in 50% of patient...
Autores principales: | Dumitriu, Bogdan, Ito, Sawa, Feng, Xingmin, Stephens, Nicole, Yunce, Muharrem, Kajigaya, Sachiko, Melenhorst, Joseph J., Rios, Olga, Scheinberg, Priscila, Chinian, Fariba, Keyvanfar, Keyvan, Battiwalla, Minoo, Wu, Colin O., Maric, Irina, Xi, Liqiang, Raffeld, Mark, Muranski, Pawel, Townsley, Danielle M., Young, Neal S., Barrett, Austin John, Scheinberg, Phillip |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721315/ https://www.ncbi.nlm.nih.gov/pubmed/26765645 http://dx.doi.org/10.1016/S2352-3026(15)00227-6 |
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