Esters of Bendamustine Are by Far More Potent Cytotoxic Agents than the Parent Compound against Human Sarcoma and Carcinoma Cells

The alkylating agent bendamustine is approved for the treatment of hematopoietic malignancies such as non-Hodgkin lymphoma, chronic lymphocytic leukemia and multiple myeloma. As preliminary data on recently disclosed bendamustine esters suggested increased cytotoxicity, we investigated representativ...

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Detalles Bibliográficos
Autores principales: Huber, Stefan, Huettner, Johannes Philip, Hacker, Kristina, Bernhardt, Günther, König, Jörg, Buschauer, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721923/
https://www.ncbi.nlm.nih.gov/pubmed/26196503
http://dx.doi.org/10.1371/journal.pone.0133743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721923/
https://www.ncbi.nlm.nih.gov/pubmed/26196503
http://dx.doi.org/10.1371/journal.pone.0133743

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