Essentiality Assessment of Cysteinyl and Lysyl-tRNA Synthetases of Mycobacterium smegmatis

Discovery of mupirocin, an antibiotic that targets isoleucyl-tRNA synthetase, established aminoacyl-tRNA synthetase as an attractive target for the discovery of novel antibacterial agents. Despite a high degree of similarity between the bacterial and human aminoacyl-tRNA synthetases, the selectivity...

Descripción completa

Detalles Bibliográficos
Autores principales: Ravishankar, Sudha, Ambady, Anisha, Swetha, Rayapadi G., Anbarasu, Anand, Ramaiah, Sudha, Sambandamurthy, Vasan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721953/
https://www.ncbi.nlm.nih.gov/pubmed/26794499
http://dx.doi.org/10.1371/journal.pone.0147188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721953/
https://www.ncbi.nlm.nih.gov/pubmed/26794499
http://dx.doi.org/10.1371/journal.pone.0147188

Ejemplares similares