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MRI of High-Glucose Metabolism Tumors: a Study in Cells and Mice with 2-DG-Modified Superparamagnetic Iron Oxide Nanoparticles

PURPOSE: This study aims to evaluate the effect of dimercaptosuccinic acid (DMSA)-coated superparamagnetic iron oxide (γ-Fe(2)O(3)@DMSA) bearing the 2-deoxy-d-glucose (2-DG) ligand on targeting tumors with high-glucose metabolism. PROCEDURES: γ-Fe(2)O(3)@DMSA and 2-DG-conjugated γ-Fe(2)O(3)@DMSA (γ-...

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Detalles Bibliográficos
Autores principales: Shan, Xiu Hong, Wang, Peng, Xiong, Fei, Gu, Ning, Hu, Hui, Qian, Wei, Lu, Hao Yue, Fan, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722088/
https://www.ncbi.nlm.nih.gov/pubmed/26150194
http://dx.doi.org/10.1007/s11307-015-0874-0