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Fatal Leishmaniasis in the Absence of TNF Despite a Strong Th1 Response

Induction of inducible nitric oxide synthase in mononuclear phagocytes by IFN-γ and innate tumor necrosis factor (TNF) provide the basis for an effective immune response to the intracellular parasite Leishmania (L.) major. In previous experiments, we observed a fatal visceral form of leishmaniasis i...

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Detalles Bibliográficos
Autores principales: Fromm, Phillip D., Kling, Jessica C., Remke, Annika, Bogdan, Christian, Körner, Heinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722107/
https://www.ncbi.nlm.nih.gov/pubmed/26834705
http://dx.doi.org/10.3389/fmicb.2015.01520