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Fatal Leishmaniasis in the Absence of TNF Despite a Strong Th1 Response
Induction of inducible nitric oxide synthase in mononuclear phagocytes by IFN-γ and innate tumor necrosis factor (TNF) provide the basis for an effective immune response to the intracellular parasite Leishmania (L.) major. In previous experiments, we observed a fatal visceral form of leishmaniasis i...
Autores principales: | Fromm, Phillip D., Kling, Jessica C., Remke, Annika, Bogdan, Christian, Körner, Heinrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722107/ https://www.ncbi.nlm.nih.gov/pubmed/26834705 http://dx.doi.org/10.3389/fmicb.2015.01520 |
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