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cAMP induction by ouabain promotes endothelin-1 secretion via MAPK/ERK signaling in beating rabbit atria
Adenosine 3',5'-cyclic monophosphate (cAMP) participates in the regulation of numerous cellular functions, including the Na(+)-K(+)-ATPase (sodium pump). Ouabain, used in the treatment of several heart diseases, is known to increase cAMP levels but its effects on the atrium are not underst...
Autores principales: | Peng, Li-qun, Li, Ping, Zhang, Qiu-li, Hong, Lan, Liu, Li-ping, Cui, Xun, Cui, Bai-ri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Physiological Society and The Korean Society of Pharmacology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722196/ https://www.ncbi.nlm.nih.gov/pubmed/26807018 http://dx.doi.org/10.4196/kjpp.2016.20.1.9 |
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