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Large adipocytes function as antigen-presenting cells to activate CD4(+) T cells via upregulating MHCII in obesity

BACKGROUND/OBJECTIVES: Although obesity is associated with low-grade inflammation and metabolic disorders, clinical studies suggested some obese people were metabolically healthy with smaller adipocyte size compared with metabolically abnormal obese (MAO). This indicated adipocyte size may be an imp...

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Detalles Bibliográficos
Autores principales: Xiao, L, Yang, X, Lin, Y, Li, S, Jiang, J, Qian, S, Tang, Q, He, R, Li, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722243/
https://www.ncbi.nlm.nih.gov/pubmed/26248660
http://dx.doi.org/10.1038/ijo.2015.145