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Large adipocytes function as antigen-presenting cells to activate CD4(+) T cells via upregulating MHCII in obesity
BACKGROUND/OBJECTIVES: Although obesity is associated with low-grade inflammation and metabolic disorders, clinical studies suggested some obese people were metabolically healthy with smaller adipocyte size compared with metabolically abnormal obese (MAO). This indicated adipocyte size may be an imp...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722243/ https://www.ncbi.nlm.nih.gov/pubmed/26248660 http://dx.doi.org/10.1038/ijo.2015.145 |