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Obesity reduces the pro-angiogenic potential of adipose tissue stem cell-derived extracellular vesicles (EVs) by impairing miR-126 content: impact on clinical applications

BACKGROUND/OBJECTIVES: Soluble factors and cell-derived extracellular vesicles (EVs) are crucial tissue repair mediators in cell-based therapy. In the present study, we investigate the therapeutic impact of EVs released by adipose tissue-derived stem cells (ASCs) recovered from obese subjects'...

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Detalles Bibliográficos
Autores principales: Togliatto, G, Dentelli, P, Gili, M, Gallo, S, Deregibus, C, Biglieri, E, Iavello, A, Santini, E, Rossi, C, Solini, A, Camussi, G, Brizzi, M F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722244/
https://www.ncbi.nlm.nih.gov/pubmed/26122028
http://dx.doi.org/10.1038/ijo.2015.123