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Novel c-Met inhibitor suppresses the growth of c-Met-addicted gastric cancer cells

BACKGROUND: c-Met signaling has been implicated in oncogenesis especially in cells with c-met gene amplification. Since 20 % of gastric cancer patients show high level of c-Met expression, c-Met has been identified as a good candidate for targeted therapy in gastric cancer. Herein, we report our new...

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Detalles Bibliográficos
Autores principales: Park, Chi Hoon, Cho, Sung Yun, Ha, Jae Du, Jung, Heejung, Kim, Hyung Rae, Lee, Chong Ock, Jang, In-Young, Chae, Chong Hak, Lee, Heung Kyoung, Choi, Sang Un
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722623/
https://www.ncbi.nlm.nih.gov/pubmed/26801760
http://dx.doi.org/10.1186/s12885-016-2058-y