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MIR494 reduces renal cancer cell survival coinciding with increased lipid droplets and mitochondrial changes

BACKGROUND: miRNAs can regulate cellular survival in various cancer cell types. Recent evidence implicates the formation of lipid droplets as a hallmark event during apoptotic cell death response. It is presently unknown whether MIR494, located at 14q32 which is deleted in renal cancers, reduces cel...

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Detalles Bibliográficos
Autores principales: Dutta, Punashi, Haller, Edward, Sharp, Arielle, Nanjundan, Meera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722626/
https://www.ncbi.nlm.nih.gov/pubmed/26794413
http://dx.doi.org/10.1186/s12885-016-2053-3